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Identification:
Name: John
Fistere
Address: 11290 Lorena Lane
Line2:
City: El
Cajon
State: CA
ZIP/PostCode: 92020
Country: USA
DayPhone: (619) 447-1907
EvePhone: (619) 447-1907
FAX:
(619) 447-1414
EMail: JFistere@cox.net
BirthDate: 5/22/35
DiagnosisDate: 8/21/95
Other: Pager:
(619) 896-1820
Medical:
ProstateVolume:
Gleason: 5+4=9
ClinicalStage: T3cN0MX
Ploidy: diploid
Partin:
Narayan:
Options:
Graph: Med PSA
Graph: Linear PSA Linear
Graph: LinRecent PSA Linear 01-Jan-1998
Graph: Recent PSA 01-Jan-1996
Graph: RP PSA 01-Jan-1996 01-Jan-1998
USADates:
NoDoublingLine:
DefaultVar: PSA
21-Sep-90 Proc: Vas Vasectomy
9-Sep-91: PSA 2.0
16-Jan-92 Diag: AbUS neg Details:
Abdominal ultrasound. Reason: Chronic high liver function,
averages: GGTP=132, Alk Phos=132 Impression: Caliectasis, left lower
pole of the kidney with possible 2cm peripelvic cyst. Otherwise normal
abdominal ultrasound.
1-May-1992: Diag: TrusBx neg
26-Feb-93 PSA 3.3
24-Feb-94 PSA = 3.1
16-Jun-95 Diag: AbUS Details:
Abdominal ultrasound for liver. Negative
21-Aug-95: PSA 5.4 Diag: DRE pos Details:
palpable, left side.
28-Feb-96: PSA 18.8
7-May-96: -Dx age 61: Diag: TRUSBx pos Details:
Section A, Right prostate: Five tan to white needle
cores of benign prostatic tissue. No malignant cells are identified.
Section B, Left prostate: Four needle cores of benign prostate glands and
stroma with tiny separate fragment containing a sheet of fused glands of
adenocarcinoma consistent with Gleason grade 4,4. There is no stroma
in this tiny fragment of cancer. Section C, Left seminal vesicle:
Five friable cores of poorly differentiated adenocarcinoma largely arranged
in sheets of fused glands similar to that described for the left prostate
biopsy. The residual fragments of stroma contain an occasional malignant
gland, as well, althogh there is no seminal vesicle identified.
17-May-96: Diag: BScan neg Details:
Bone Scan: No areas of uptake are present to suggest metastatic
disease. Mild degenerative uptake is present in the left hip.
28-May-96: PSA 39.2 RT-PCR-PSA neg
29-May-96: Proc: RP, Details:
SURGERY: It was noted that the left seminal vesicle
was adherent along its lateral margin and there was difficulty in reflecting
the seminal vesicle off of the rectal wall.
PATHOLOGY: 5 samples. 1. Right obturator region.
lymph node dissection: Four lymph nodes and associate soft tissue.
Negative for tumor. 2. Left obturator region, lymph node dissection:
Five lymph nodes and associated soft tissue, negative for tumor.
3. Region of left seminal vesicle, excisional biopsy: Multiple fragments
of high grade adenocarcinoma of prostate, Gleason 4+5=9. 4. Prostate gland
and seminal vesicle, radical retropubic prostatectomy: Extensive adenocarcinoma
of prostate, poorly differentiated (Gleason grade 4+4=8), involving right
and left prostatic lobes and both seminal vesicles. 5. Distal left
seminal vesicle, excisional biopsy: Portions of benign seminal vesicle.
Prostate, prostatectomy: Adenocarcinoma
Grade (Gleason): 4+4=8
Size: 1.5 cm in both right and left lobes.
Extent of involvement: Extensive, greater than 50%
of prostate
Capsular penetration: Absent
Peripheral margin involvement: Absent
Proximal and distal margins: Negative
Seminal vesicle involvement: Bilateral and extensive
Lymph node involvement: Absent
Pathologic staging (TNM): T3cN0Mx
Clinical Stage: T3cN0MX Ploidy: diploid
25-Jun-96: PSA=30.2 (4-week post-RP) :-(
Liver: SSGPT/ALT 54 (vs 0-40) GGT 260 (vs 11-65)
Alk Phos 314 (vs 39-117)
8-Jul-96: PSA=28.6
8-Jul-96 Diag: Ploidy Details:
Flow cytometry from paraffin block. DNA index/ploidy:
1.0/diploid S-phase fraction: 8.0%
11-Jul-96: Diag: MRI-S pos Details:
There are minimal foci of increased signal on T1 weighted
sequences in the prostate bed which may represent residual hemorrage.
There is no evidence of bony lesions or adenopathy. Amorphous tissue
is seen in the prostate bed, likely representing granulation tissue or
residual tumor. No mass is identifed. Foci of increased signal
are seen in the region of the seminal vesicles, which have a cystic appearance,
likely representing some residual seminal vesicle.
On spectroscopy, slightly elevated choline-to-citrate
ratios are identified in a few voxels representing a small amount of residual
tumor. 7-9cc of tissue.
19-Jul-96: PSA=37.8 :-( PAP=6.8
Liver: ALT 43 (vs 0-40) GGT 246 (vs 11-65) Alk Phos
230 (vs 39-117)
19-Jul-96: Started Casodex 50 mg/day
19-Jul-96: Started Proscar 5 mg/day
22-Jul-96: Diag: AbCT neg Details:
Abdominal CT scan: Reason: Abnormal LFT. Computed
axial tomography is performed of the abdomen prior to and following 125cc
of Optiray-320 as well as following oral contrast material. Examination
of the liver fails to demonstrate a definite abnormality. The pancreas
is not enlarged at this time. The periaortic area shows no evidence
of any lymphadenopathy. The renal margins show some lipomatous changes
in the region of the left kidney. There is a density closely related
to the dorsal surface of the left kidney, although it appears to be separate
from it, and probably represents some averaging from the spleen.
IMPRESSION: No abnormalities detected on computed axial tomography of the
abdomen.
25-Jul-96: Started Lupron
30-Jul-96: PSA=19.2 RT-PCR-PSA negative
6-Aug-96: Started MCP modified citrus pectin, 5-15 grams per day
22-Aug-96: Diag: BS neg Bone scan negative
26-Aug-96: PSA=1.2 PAP=2.
Liver: ALT 69 (vs 0-40) GGT 292 (vs 11-65) Alk Phos
214 (vs 39-117) :-(
12-Sep-96: Stopped Casodex because of high liver function
20-Sep-96: PSA=0.2 PAP=1.7 Added soy and stewed
tomatoes to low fat diet.
22-Oct-96: Switched to Quest Corning Ultrasensitive, Test Code 60492"
22-Oct-96: PSA=0.1 PAP=1.
21-Nov-96: PSA=0.09
25-Nov-96: Diag: ProstSc neg ProstaScint Negative
23-Dec-96: PSA=0.07
27-Jan-97: PSA=0.02 :-) SSGPT/ALT=100 :-(
26-Feb-97: PSA=0.03 SSGPT/Alt=66
22-Mar-97: Diag: MRI-S neg Details:
MRI with Spectroscopy at UCSF
1. No evidence of recurrent disease
2. Spectrosopy demonstrates no metabolically active
tissue.
24-Mar-97: PSA=0.01
28-Mar-97: Proc: Implant Details:
Mentor Mark II inflatable implant installed
28-Apr-97: PSA=<0.007
2-Jun-97: PSA=<0.007
26-Aug-97: PSA=<0.007
26-Aug-97: PSA=0.007 Note: < missing.
26-Aug-97: Stopped Lupron, continuing Proscar.
7-Oct-97: PSA=<0.007 :-) Liver functions up a little.
:-(
31-Oct-97: PSA=0.1 :-( Liver functions heading down, most OK
:-)
3 Nov 97 Diag: BDens neg Details:
The bone mineral density of the femoral neck is 0.925
gm/cm2. This represents 1.2 standard deviations below the young normal
population control (T-score), and 0.3 standard deviations below the age/sex
matched reference in the patient's ethnic group (Z-score).
The bone mineral density of the A-P spine from L2
to L4 is 1.224 gm/cm2. This represents 0.1 standard deviations below the
young normal population control (T-score), and 0.1 standard deviations
above the age/sex matched reference in the patient's ethnic group (Z-score).
This study shows bone mass that is less than the
adult normal, but considered normal for the patient's age.
17-Nov-97: PSA=0.02 :-)
17-Dec-97 PSA 0.01
9-Feb-98 PSA 0.007
25-Mar-98 PSA 0.1
20-Apr-98 PSA 0.01
20-Apr-98 PSA 0.01
17-Jun-98 PSA 0.02
11-Aug-98 PSA 0.02
19-Aug-98 Stopped Proscar
15-Sep-98 <0.007
23-Nov-98 0.07
5-Jan-99 0.02
27-May-99 0.04
12-Nov-99 0.11
19-Jan-00 0.17
13-Jun-00 0.03
Notes:
Low-fat, low red meat diet includes daily soy milk/tofu/modified
citrus pectin shakes, stewed tomatoes with a little olive oil, multivitamins,
extra A, C, E, calcium, selenium, Ginko Biloba, Coenzyme Q-10, and
green tea extract.
End:
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