Basic ideas:
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This page will give ideas of ways you can arrange arcade games.
Still figuring this out, getting RGVAC input.

Best suggestion: Map out the gameroom on grid paper
  Props to Curtis Hart for this well-formed idea
  TODO: Make a grid and pre-formed games to simply print out.
  Use wide-ruled grid paper
  1 square = 1 foot is generally good
  1 square = 6 inches is easier to draw with, but easier to make mistakes
  Draw in steps, poles, cabinets or anything else that is not usable floor space.
  Draw in arcs, if necessary, to show the space covered when a door is opened.
  Draw any other obstacles which may affect game placement
  Draw in electrical outlet availability
  Create cutouts of anything you're wanting to arrange.
    Arcade games (upright, cocktail, cockpit, mini)
    Pinball machines
    Air Hockey, Pinball, Foos Ball, Ping-Pong table
    Furniture (chairs, tables, bar, etc).
    Pool table
      Massive space hogs.
      You must allow a buffer zone around the table.
      Buffer zone prevents things/people getting poked with cue sticks.
    Other items
      Pop/Soda/Coke Machine
      Vending Machine
      Display case

Be sure to leave a good walking space.
  A comfortable walking area is at least 3 feet wide.
  Need more space for isles with games on both the left and the right.

Backs against the wall.
  Efficient use of space
  Traditional layout.
  Often used when space is at a premium.
  Games have to be pulled out to be serviced.

Slanted backs against the wall.
  Bill Maier (neverendz@aol.com)
  Same as backs against the wall, except games are turned 20-45 degrees.
  Shows off the side art.
  Not much more space.
  Easier for service if space is placed between and/or behind games.

Back-to-back games
  Place two rows of games where their backs face each other.
  Efficient use of space.

Circle facing outwards
  A number of games put into a small circle (or square), facing the outside.
  Can be useful for breaking up a space.
  Utilization of a single power source in the center.
  Something tall and visual should be put in the center. [specific idea here]