SAGE KE 2004

Once More, With Feeling Hobbling glycation-detecting protein restores feeling in diabetic mice. (22 December 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (51), nf116. [DOI: 10.1126/sageke.2004.51.nf116]
[Abstract] [Full text]

Natural Foods Wild-like pattern of feast and famine extends Medfly life span. (22 December 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (51), nf114. [DOI: 10.1126/sageke.2004.51.nf114]
[Abstract] [Full text]

Paying the Price Long-lived worms can't compete. (1 December 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (48), nf107. [DOI: 10.1126/sageke.2004.48.nf107]
[Abstract] [Full text]

Young at Heart Life-extending mutation preserves fly hearts. (24 November 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (47), nf105. [DOI: 10.1126/sageke.2004.47.nf105]
[Abstract] [Full text]

Culture Clash Yeast cells might sign suicide pact, but the idea remains controversial. (17 November 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (46), ns9. [DOI: 10.1126/sageke.2004.46.ns9]
[Abstract] [Full text] [PDF]

Solving the Energy Crisis Signaling molecule spurs cells to generate mitochondria. (17 November 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (46), nf101. [DOI: 10.1126/sageke.2004.46.nf101]
[Abstract] [Full text]

Prey for Long Life The hunted don't necessarily age quickly. (27 October 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (43), nf97. [DOI: 10.1126/sageke.2004.43.nf97]
[Abstract] [Full text]

Wilting Weed? Arabidopsis might provide new insights into workings of protein linked to a premature aging disease. (20 October 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (42), nf93. [DOI: 10.1126/sageke.2004.42.nf93]
[Abstract] [Full text]

Homing In on a Hormone Fat-based molecules divert nematodes from survival mode. (13 October 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (41), nf92. [DOI: 10.1126/sageke.2004.41.nf92]
[Abstract] [Full text]

Fanning the Flames Telomerase aggravates oxidative damage in mitochondria. (6 October 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (40), nf90. [DOI: 10.1126/sageke.2004.40.nf90]
[Abstract] [Full text]

Knife Jugglers Painkillers shift Alzheimer's protein slicer. (29 September 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (39), nf89. [DOI: 10.1126/sageke.2004.39.nf89]
[Abstract] [Full text]

Acid Trip Blocking pH-sensitive calcium channels prevents stroke damage. (22 September 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (38), nf87. [DOI: 10.1126/sageke.2004.38.nf87]
[Abstract] [Full text]

Tarnished Vision Iron glut clouds eyes in aging mice. (15 September 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (37), nf85. [DOI: 10.1126/sageke.2004.37.nf85]
[Abstract] [Full text]

Leashing Leishmania Some old mice fight parasitic infection better than young mice do. (8 September 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (36), nf82. [DOI: 10.1126/sageke.2004.36.nf82]
[Abstract] [Full text]

Regenerating Regeneration Classic models illuminate possible ways to rejuvenate human tissues. (1 September 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (35), ns6. [DOI: 10.1126/sageke.2004.35.ns6]
[Abstract] [Full text] [PDF]

Hastening Death to Delay Aging New approach speeds hunt for manipulations that retard fly decrepitude. (1 September 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (35), nf81. [DOI: 10.1126/sageke.2004.35.nf81]
[Abstract] [Full text]

Going the Extra Mile Molecular manipulations turn ordinary mice into athletic stars. (25 August 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (34), nf79. [DOI: 10.1126/sageke.2004.34.nf79]
[Abstract] [Full text]

Longevity Is Infectious Bacteria foster long life in young flies. (25 August 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (34), nf78. [DOI: 10.1126/sageke.2004.34.nf78]
[Abstract] [Full text]

Hardy Helper Molecular partner urges worm protein to trigger survival pathway. (18 August 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (33), nf76. [DOI: 10.1126/sageke.2004.33.nf76]
[Abstract] [Full text]

Eating Yourself to Life Signaling mechanisms that delay death induce starvation response in fruit flies. (11 August 2004)
John Davenport
Sci. Aging Knowl. Environ. 2004 (32), nf74. [DOI: 10.1126/sageke.2004.32.nf74]
[Abstract] [Full text]

The Thing That Wouldn't Leave Immune cells that flock to fat-laden blood vessels stay when they should go. (4 August 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (31), nf72. [DOI: 10.1126/sageke.2004.31.nf72]
[Abstract] [Full text]

Growing Pains As researchers sort through the hype surrounding growth hormone, they hope to uncover the molecule's actual benefits. (28 July 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (30), ns5. [DOI: 10.1126/sageke.2004.30.ns5]
[Abstract] [Full text] [PDF]

(Data)base Desires New resource compiles genes that potentially influence human aging. (28 July 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (30), nf69. [DOI: 10.1126/sageke.2004.30.nf69]
[Abstract] [Full text]

Long in the Tooth Paleolithic hominids outlived their predecessors, dental wear suggests. (14 July 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (28), nf66. [DOI: 10.1126/sageke.2004.28.nf66]
[Abstract] [Full text]

A Twist in an Early End Snafus in telomere unwinding foster a premature aging syndrome. (7 July 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (27), nf63. [DOI: 10.1126/sageke.2004.27.nf63]
[Abstract] [Full text]

On Trial Jumping from laboratory to human studies puts researchers to the test. (16 June 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (24), oa1. [DOI: 10.1126/sageke.2004.24.oa1]
[Abstract] [Full text] [PDF]

Too Much of a Good Thing Extra doses of antioxidant protein spur insulin resistance. (16 June 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (24), nf58. [DOI: 10.1126/sageke.2004.24.nf58]
[Abstract] [Full text]

Peer Pressure Clustering sways antioxidant enzyme toward new behavior. (2 June 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (22), nf56. [DOI: 10.1126/sageke.2004.22.nf56]
[Abstract] [Full text]

Merging Routes Multiple paths lead to senescence. (26 May 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (21), nf54. [DOI: 10.1126/sageke.2004.21.nf54]
[Abstract] [Full text]

Calorie Restriction Un-SIR-tainty Yeast don't need SIR2 to starve their way to long life. (12 May 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (19), nf48. [DOI: 10.1126/sageke.2004.19.nf48]
[Abstract] [Full text]

From Womb the Bell Tolls Stressing a fetus creates health problems that persist into old age. (28 April 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (17), nf44. [DOI: 10.1126/sageke.2004.17.nf44]
[Abstract] [Full text]

Lethal Leak Protein that shortens mouse life span opens holes in mitochondria. (21 April 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (16), nf43. [DOI: 10.1126/sageke.2004.16.nf43]
[Abstract] [Full text]

Fork in the Road Separate branches in insulin-related signaling pathway control worm hibernation and life span. (14 April 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (15), nf40. [DOI: 10.1126/sageke.2004.15.nf40]
[Abstract] [Full text]

The Flavor of Aging As researchers decipher why the ability to smell and taste deteriorates in the elderly, they hope to uncover ways to make aging more palatable. (24 March 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (12), ns1. [DOI: 10.1126/sageke.2004.12.ns1]
[Abstract] [Full text] [PDF]

Greasing the Way for Bone Growth Signaling molecule steers cells toward bone and away from fat. (17 March 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (11), nf30. [DOI: 10.1126/sageke.2004.11.nf30]
[Abstract] [Full text]

Hop on Board Blueprint for fat-cell specialization hitches a ride from a shuttle protein. (17 March 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (11), nf29. [DOI: 10.1126/sageke.2004.11.nf29]
[Abstract] [Full text]

Throwing Fat on the Fire Mice lacking supposed insulin enabler are surprisingly lean. (17 March 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (11), nf27. [DOI: 10.1126/sageke.2004.11.nf27]
[Abstract] [Full text]

Copper Stopper Obliterating a metal transporter immortalizes a fungus. (3 March 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (9), nf25. [DOI: 10.1126/sageke.2004.9.nf25]
[Abstract] [Full text]

Overcoming Inertia Inflammation gives neurons a shove when a cellular brake releases. (25 February 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (8), nf22. [DOI: 10.1126/sageke.2004.8.nf22]
[Abstract] [Full text]

Cell Death, Start to Finish Nitric oxide and zinc cooperate to demolish overexcited neurons. (11 February 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (6), nf17. [DOI: 10.1126/sageke.2004.6.nf17]
[Abstract] [Full text]

A Turn From the Worm Human version of worm longevity protein shuts off rather than activates gene regulator. (11 February 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (6), nf16. [DOI: 10.1126/sageke.2004.6.nf16]
[Abstract] [Full text]

Tugging at Heartstrings Protein associated with heart abnormalities and premature aging syndrome transmits mechanical stress to the nucleus. (4 February 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (5), nf15. [DOI: 10.1126/sageke.2004.5.nf15]
[Abstract] [Full text]

Plaque Attack Mice without ApoE and related protein unexpectedly accumulate ß-amyloid deposits. (28 January 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (4), nf12. [DOI: 10.1126/sageke.2004.4.nf12]
[Abstract] [Full text]

Skeleton Key Lipid-processing enzyme weakens bones. (14 January 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (2), nf7. [DOI: 10.1126/sageke.2004.2.nf7]
[Abstract] [Full text]

UnSIRtainty Principle Conflicting results underscore questions about how calorie restriction activates yeast longevity enzyme. (7 January 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (1), nf5. [DOI: 10.1126/sageke.2004.1.nf5]
[Abstract] [Full text]

Picky Eater Gluttonous cellular recycler hungers for damaged proteins. (7 January 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (1), nf2. [DOI: 10.1126/sageke.2004.1.nf2]
[Abstract] [Full text]

TORquing Toxins Extra doses of movement-disorder protein guard neurons against poisons. (7 January 2004)
R. John Davenport
Sci. Aging Knowl. Environ. 2004 (1), nf1. [DOI: 10.1126/sageke.2004.1.nf1]
[Abstract] [Full text]